4-Bromo-pyridine-2-carboxylic acid ethyl ester

4-Bromo-pyridine-2-carboxylic acid ethyl ester - Names and Identifiers

Name	4-Bromo-pyridine-2-carboxylic acid ethyl ester
Synonyms	ethyl 4-broMopicolinate Ethyl 4-bromopyridine-2-carboxylate 4-Bromo-pyridine-2-carboxylic acid ethyl ester 2-Pyridinecarboxylic acid, 4-broMo-, ethyl ester
CAS	62150-47-4

4-Bromo-pyridine-2-carboxylic acid ethyl ester - Physico-chemical Properties

Molecular Formula	C8H8BrNO2
Molar Mass	230.06
Density	1.501±0.06 g/cm3(Predicted)
Melting Point	43 - 44oC
Boling Point	299.3±20.0 °C(Predicted)
Solubility	Chloroform (Slightly), Methanol (Slightly)
pKa	-0.11±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C

4-Bromo-pyridine-2-carboxylic acid ethyl ester - Introduction

Acid ethyl ester is an organic compound with the chemical formula C8H8BrNO2.

Its properties are as follows:
Appearance: colorless liquid
Melting point:-9 ℃
Boiling point: 220-222 ℃
Density: 1.41g/cm3
Solubility: Soluble in most organic solvents, such as ethers and alcohols.

The main use of this compound is as an important intermediate in organic synthesis. It can be used to synthesize organic compounds such as drugs, pesticides and agrochemical reagents. It has a wide range of applications in the field of drug synthesis, can be used as antibiotics, anti-cancer drugs and a variety of tonic synthetic intermediates.

The preparation method of acid ethyl ester is generally obtained by reacting 4-bromopyridine and ethyl formate under suitable reaction conditions. The specific synthesis method can be optimized according to the requirements and conditions.

You need to pay attention to safety precautions when using and handling acid ethyl ester. It is an organic solvent that is volatile and flammable, so it should be kept away from open flames and high temperatures. At the same time, you should avoid inhaling vapors and avoid direct contact with skin and eyes. Wear appropriate protective equipment, such as gloves, safety glasses and protective face masks, during use or handling. If exposed or inhaled, rinse immediately with clean water and seek medical help. During storage, it should be kept in a closed container and placed in a cool and dry place.

Last Update：2024-04-09 21:11:58